Protein-Protein Intraction Network Analysis

Comparison of Tumor and Normal Cells Protein-Protein Interaction Network Parameters

Dataset

The dataset originally is from the following paper, but we had a preprocessing and split it into the different CSV files based on the normal and cancer cells.

Rahman, KM Taufiqur, et al. "Changes in protein interaction networks between normal and cancer conditions: Total chaos or ordered disorder?", Network Biology, 2013 (link)

Islam, Md Fahmid, et al. "Comparative analysis of differential network modularity in tissue specific normal and cancer protein interaction networks." Journal of clinical bioinformatics, 2013

Implementation

The analysis is implemented in R with iGraph lib.

Cite

Rahmani, H. A., Khanteymoori, A. R., & Olyaee, M., Comparison of Tumor and Normal Cells Protein-Protein Interaction Network Parameters, the 6th Iranian Conference on Bioinformatics, University of Tehran, Tehran, Iran, 2016 (link)

Webpage

Protein-Protein Interaction Network Analysis (Normal and Cancerous cells)